U.S. ARMY INSTITUTE OF SURGICAL RESEARCH
"Optimizing Combat Casualty Care"

Clinical Trials in Burns and Trauma (CTBT)


RESEARCH FOCUS

Our research effort focuses on clinical trials that improve functional survival in military and civilians who sustain burn injury and/or associated trauma. We achieve this by focusing on studies designed to improve clinical care from time of initial injury, acute hospital treatment, to discharge and throughout long-term outpatient rehabilitation.


RESEARCH GOALS

To improve standard of care and provide-state-of-the art hospital care to burn and trauma victims by addressing:

  • Optimization of wound healing
  • Prevention, early detection, and treatment of organ failure
  • Rehabilitation
  • Reconstruction
  • Resilience

CORE COMPETENCIES

  • Good Clinical Practice
  • Human Research
  • Burn and Trauma Intensive Care
  • Clinical Trials
  • Epidemiology and Statistics

CURRENT RESEARCH EFFORTS

  • FDA regulated randomized controlled trials utilizing various skin substitutes
  • Early detection of organ failure in burns and trauma using urinary and serum biomarkers
  • Extracorporeal organ support and blood purification in sepsis and rhabdomyolysis
  • Combat Casualty Care Multicenter studies through the American Burn Association multi-center trials group

Contact the CTBT Research Director, click here.


RECENT PUBLICATIONS

Belenkiy SM, Buel AR, Cannon JW, Sine CR, Aden JK, Henderson JL, Liu NT, Lundy JB, Renz EM, Batchinsky AI, Cancio LC, Chung KK. Acute respiratory distress syndrome in wartime military burns: Application of the Berlin criteria. J Trauma Acute Care Surg. 2014 Mar;76(3):821-7. doi: 10.1097/TA.0b013e3182aa2d21.PMID:24553555[PubMed - in process.]

Linden K, Stewart IJ, Kreyer SF, Scaravilli V, Cannon JW, Cancio LC, Batchinsky AI, Chung KK. Extracorporeal blood purification in burns: A review. Burns. 2014 Feb 15. pii: S0305-4179(14)00026-6. doi: 10.1016/j.burns.2014.01.013. [Epub ahead of print] Review.

Rickard RF, Martin NA, Lundy JB. Imprecision in TBSA calculation. Burns. 2014 Feb;40(1):172-3. doi: 10.1016/j.burns.2013.09.002. Epub 2013 Sep 24. No abstract available.

Nam JJ, Chung KK, King BT, Jones JA, Cancio LC, Baer DG, Renz EM, Blackbourne LH, Orman JA. Citation classics in the burn literature during the past 55 years. J Burn Care Res. 2014 Mar-Apr;35(2):176-85. doi: 10.1097/BCR.0b013e31828cb25e.

Williams JF, King BT, Aden JK, Serio-Melvin M, Chung KK, Fenrich CA, Salinas J, Renz EM, Wolf SE, Blackbourne LH, Cancio LC. Comparison of traditional burn wound mapping with a computerized program. J Burn Care Res. 2013 Jan-Feb;34(1):e29-35. doi: 10.1097/BCR.0b013e3182676e07